adidas samba golf shoes High doses of vitamin B tied to lung cancer risk
Men who took high doses of vitamin B6 and B12 supplements had a higher risk of lung cancer, and the association was highest among current smokers, according toa study published Tuesday.
The study found a 30% to 40% increased risk of lung cancer among men taking these vitamins from individual supplements not from multivitamins or diet alone.
Current male smokers taking the highest levels of vitamin B6 had triple the risk of lung cancer over six years, compared with those who didn take supplements. For vitamin B12, that risk nearly quadrupled. These levels were more than 11 times therecommended daily amount of B6and 23 timesthat of B12.
you look at B vitamin supplement bottles they are anywhere between 50 fold the US recommended dietary allowance (to) upward of 2,100 fold, Brasky said. B12 injections have also become vogue in recent years, he said.
In smaller quantities, these vitamins are involved in several vital processes in the body, including DNA replication. But many high dose supplements, he said, claim to boost energy and provide other unproven benefits.
marketing. That not science, he said.
The study was limited to roughly 77,000 Washington state adults, ages 50 to 76. This included 139 cases of lung cancer among more than 3,200 current male smokers. Over 93% of participants were white.
There were too few cases of lung cancer among nonsmokers to include them in the full analysis. An increased risk of lung cancer was not seen among women or with the vitamin B9, also known as folate.
Other researchers have found different results. Some studies linked vitamin B6 withlower lung cancer risk, and another found that B12 hadno impacton risk. Or it may be that lung cancer itselfraises levels of these vitaminsin the body.
think it hard to say why these studies contradict each other, saidElizabeth Kantor, an epidemiologist at Memorial Sloan Kettering Cancer Center who has studied dietary supplements and cancer risk. She was not involved in the latest research. it the disease process that affects the blood levels? I think that the door remains open on that. focus on B vitamins may not be the most effective way to protect against lung cancer, experts warn.
tobacco smoke is the No. 1 most important factor, not just only in lung cancer but in many cancers, Brasky said. Lung cancer kills more Americans than any other kind of cancer.
we talking about what to be concerned about most: If you a male smoker and you want to take B vitamins, you can stop smoking, said.
is the most important thing here, and that preventable. B or not to B?
the average person in this country, it tough to be deficient in B vitamins, Brasky said.
Those who are those with anemia or celiac disease, for example will feel tired and run down. For them, supplements might help.
But taking of these supplements doesn do much for the average healthy person, Brasky said, nor does it cause immediate harm. The body tends to get rid of excess vitamin,
Stomach acid and digestion, Bailey said, are able to out B12 from food so that the body can absorb it. Some synthetic supplements, however, may be more easily absorbed.
Vitamin B12 is found inanimal productslike meat, eggs and milk. Americans getmost of their B6from fortified cereals, beef, chicken, fruits and starchy vegetables.
Too littleof these vitamins is thought to carry cancer risk, too. Errors can happen when building new strands of DNA, causing them to break.
In high concentrations, however, the exact relationship between the vitamins and lung cancer is unclear. If the vitamins are indeed responsible for increasing the lung cancer risk, Brasky said, another question would be whether B vitamins are hastening the development of a lung cancer that already there or leading to new cancers.
Bailey warned that we are nowhere close to claiming that these high dose supplements cause cancer. She added that the dietary survey the researchers used which calculated the average daily intake over the prior 10 years can be imprecise. But Brasky said that adults generally recall which supplements they taken, allowing researchers to get a good idea of their average doses.
People mostly take dietary supplements because they think they will make them healthier, not because they are trying to add nutrients to their diet, Bailey showed in a2013 study. And those who take vitamins may be hard to study, she said, because they fall into two very different categories.
my mind, people take supplements because they sick and trying to get better or because they healthy and want to stay that way, she said.
In a studyin October, Kantor showed that about half of American adults have consistently taken dietary supplements over the years. The use of B12 grew 40% from 1999 to 2012, while the use of B6 dropped by a smaller amount.
might be one reason why somebody takes something, but it can have other effects on our bodies, Kantor said. don know the whole host of effects. good news, Bailey said, is that most people aren taking the single vitamin, high dose supplements that go far beyond recommended levels.
people are taking multivitamins, she said, for that, there really been no (cancer) association,
which I think is a success story.